Xencor's XmAb819 Data Could Support Registrational Path, Wedbush Says

01:33 PM EDT, 09/25/2026 (MT Newswires) -- Xencor's (XNCR) upcoming dose-expansion data readout for XmAb819 to treat clear cell renal cell carcinoma has potential for improved response rates and more mature durability results, Wedbush Securities said in a Friday research report. XmAb819 has been evaluated in a more pretreated population, and meaningful activity in this setting could establish differentiation in efficacy and drive upside, according to the note. If the expansion cohort maintains the 25% overall response rate and 70% disease control rate already observed in dose-escalation, while dose-escalation cohorts show progression-free survival in line with or modestly above the established 6- to 7-month range, the drug remains on track for its registrational path, supporting continued appreciation of the stock, analysts wrote. Wedbush reiterated its outperform rating and a $30 price target on the stock. Price: 23.72, Change: -0.16, Percent Change: -0.69